Mucoepidermoid carcinoma. An update and review of the literature

Elemento

Título

Mucoepidermoid carcinoma. An update and review of the literature

Description

Objetivo: El carcinoma mucoepidermoide (MEC) es la neoplasia maligna de glándulas salivales más frecuente , representando del 10 al 15% de todas las neoplasias salivales. Se realizó una revisión de la literatura para determinar las tendencias en la presentación, las características diagnósticas, el tratamiento y los resultados. Métodos: Se realizó una búsqueda en PubMed, Embase y Scopus. El proceso de búsqueda fue realizado por 2 revisores independientes y los criterios de inclusión incluyeron revisiones sistemáticas, metanálisis, estudios de casos y controles, estudios de cohortes , estudios comparativos, ensayos clínicos, estudios transversales, estudios descriptivos, estudios experimentales, informes de casos, informes de casos. estudios en serie y estudios en humanos que evalúan MEC. Resultados: El sexo femenino fue más afectado (54,5%) y la edad promedio fue de 48,8 años. La localización más frecuente de MEC fue en las glándulas parótidas (56,8 %) seguida del paladar duro (18 %). La presentación clínica más frecuente fue la masa (65,2 %) seguida de la úlcera (29,4 %) con la presión como síntoma principal (64,4 %). La presentación histológica más frecuente fue de Bajo grado (46,7%) seguida de Intermedio (27,3%) y el tratamiento más utilizado fue la cirugía (76,2%). El seguimiento promedio fue de 138,5 meses y se informó una recurrencia del 8,5%. Conclusión: La MEC mostró una fuerte predilección por las glándulas parótidas, es frecuentemente dolorosa, se presenta con mayor frecuencia como una masa y con mayor frecuencia tiene una presentación histológica de bajo grado.

Relation

Grupo de Ciencias Odontológicas Unicoc

Creator

Beltran Gutierrez, Jimmi Ricardo

Peraza, A.

Gomez, R.

Amarista, F.J

Mediator

Centro de Investigación Colegio Odontológico - CICO

Date Issued

2020-12-01

Abstract

Objective: Mucoepidermoid Carcinoma (MEC) is the most common malignant salivary gland neoplasm, representing 10 to 15% of all salivary neoplasms. A review of the literature was conducted in order to determine trends in presentation, diagnostic features, treatment, and outcomes. Methods: A PubMed, Embase, and Scopus search was carried out. The search process was performed by 2 independent reviewing authors and inclusion criteria included systematic reviews, meta-analyses, case-controls studies, cohort studies, comparative studies, clinical trials, cross-sectional studies, descriptive studies, experimental studies, case reports, case series studies, and human studies evaluating MEC. Results: Females were more affected (54.5%) and the average age was 48.8 years. The most common location of MEC was the parotid glands (56.8%) followed by hard palate (18%). The most frequent clinical presentation was mass (65.2%) followed by ulcer (29.4%) with pressure as their main symptom (64.4%). The most frequent histologic presentation was Low grade (46.7%) followed by Intermediate grade (27.3%) and the most used treatment was surgery (76.2%). The average follow up was 138.5 months, and recurrence was reported at 8.5%. Conclusion: MEC showed a strong predilection for the parotid glands is frequently painful, most frequently presents as a mass and most commonly has a low-grade histologic presentation

Extent

8 pp.

Format

application/pdf

doi

https://doi.org/10.1016/j.jormas.2020.06.003

issn

2468-7855

Lenguaje

Inglés

Publisher

Société Française de Stomatologie, Chirurgie Maxillo-Faciale Chirurgie Orale

page end

720

issue

6

page start

713

Fuente

Journal of Stomatology, Oral and Maxillofacial Surgery

Repositorio Institucional Unicoc - RI-Unicoc

volume

121

Is Part Of

Journal of Stomatology, Oral and Maxillofacial Surgery, ISSN: 2468-7855, Vol. 121, No. 6, (Diciembre 2020);pp. 713-720

uri

https://www.sciencedirect.com/science/article/abs/pii/S2468785520301488

Access Rights

restrictedAccess

Bibliographic Citation

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primary topic

Research Subject Categories::ODONTOLOGY::Oral pathology and forensic odontology

Subject

Cáncer

Mucoepidermoid carcinoma

Salivary glands

Review article

Carcinoma mucoepidermoide

Cáncer

Glándulas salivales

Articulo de revisión

Alternative Title

Carcinoma mucoepidermoide. Una actualización y revisión de la literatura.

Tipo

Artículo

current project

Grupo de Ciencias Odontológicas Unicoc

number of pages

8 pp.

Identifier

https://www.sciencedirect.com/science/article/abs/pii/S2468785520301488

Colecciones

Centro de Investigación Colegio Odontológico - CICO